‘Miracle’ cures face extinction

From a desert succulent that may ‘cure’ obesity, to a Chinese magnolia effective against previously untreatable cancers, hundreds of the planet’s most promising medicinal plants are facing an imminent threat, warn world’s experts.

Looming Health Care Crisis: A new global study reveals that hundreds of medicinal plant species, whose naturally-occurring chemicals make up the basis of over 50% of all prescription drugs, are threatened with extinction. Sparking off fears of a global health care crisis, a consortium of leading experts acting through London-based organisation, Botanic Gardens Conservation International (BGCI), are calling for urgent action to help ‘secure the future of global healthcare’.

With 70% of all newly-developed drugs in the United States, the world’s largest and wealthiest pharmaceuticals market, being derived from natural sources, it is clear that despite major scientific advances, the future of human healthcare is still overwhelmingly reliant on the plant kingdom.

“We are using up a wide range of the world’s natural medicines and squandering the potential to develop new remedies“ says Sara Oldfield, Secretary General of BGCI “And yet it is perfectly possible to prevent plant extinctions”.

There was a time when scientists predicted that developments in biochemistry would mean that most if not all new drugs would be simply synthesised in the lab, however in recent years it has become increasingly clear that this is unlikely to happen. For while scientists are able to artificially replicate several medicinally-active compounds found in plants, a overwhelming number of these are still eluding all attempts to copy them, or it is simply not commercially viable to do so.

Take the world’s most widely-used cancer drug, Paclitaxel, for instance. Derived from the bark of several species of yew trees, its complex chemical structure and biological function has defied all attempts of commercial synthesis, gaining it the reputation for being “the kind of drug that would be impossible to design from scratch”. Yet with, until very recently, an average of 6 trees needed for just a single dose, its use has decimated wild yew populations across the world, with 80% of the trees in China’s Yunnan Province, once famous for its yew forests, destroyed within a three year period. “The dramatic decline in a range of yew species, highlights the global extinction crisis that is facing medicinal plant species.” says Oldfield.

Nowhere is this dependence on medicinal plants more acute than in developing countries, with the World Health Organisation estimating that an astonishing 80% of the global population, some 5.3 billion people, rely on traditional plant-based medicine as their primary form of healthcare, and in many cases collection and sales of these plants provide their only form of livelihood. Yet it is exactly in these areas that these plants are under most threat, putting the rural poor at the sharp end of the looming healthcare crisis.

“The loss of the world’s medicinal plants may not always be at the forefront of the public consciousness, however it is not an overstatement to say that if the precipitous decline of these species is not halted, it could destabilise the future of global healthcare, putting many millions of lives at risk.” reports Belinda Hawkins the report author.

BGCI
Descanso House,
199 Kew Road,
Richmond, Surrey
TW9 3BW, UK
www.bgci.org